Sulfobutyl Beta- Cyclodextrin/Sbecd CAS 182410-00-0 CAS 194615-04-8

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Model NO.: USP BP EP
• Certification: ISO 9001, USP, BP
• State: Powder
• Purity: >99%
• Product Name: Sulfobutyl Beta- Cyclodextrin
• Appearance: White Powder
• Sample: 10~20 Free
• Test Method: HPLC
• Transport Package: 1kg/Bag; 25kg/Drum
• Specification: Top grade
• Trademark: JULY
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product Description

 

Product Name	Factory Supply sulfobutyl beta- cyclodextrin/SBECD
CAS No.	182410-00-0 194615-04-8
Appearance	White Powder
Purity	98.0% --101.0%
Main application	It is suitable for solubilization and solubilization of injection drugs
Route of administration	Injection medicine, oral medicine, nasal medicine and eye medicine have special affinity and inclusion property for nitrogen-containing drugs.
Quality standard	USP43-NF38

Sulfobutyl beta- cyclodextrindetection standard
Inspection items	USP43-NF38
character	White to off-white,amorphous powder.
Identification	IR	Same absorption bands as USP betadex sulfobutyl ether sodium RS.
	HPLC	The retention time of the major peak of sample solution corresponds to the standard solution.
	Average Degree of Substitution	Conform
	Sodium	Identify test are positive for Sodium

Assay	95.0%~105.0%
Beta Cyclodextrin	≤0.1%
1,4-Butane Sultone	≤0.5ppm
Sodium Chloride	≤0.2%
4-Hydroxybutane-1-sulfonic Acid	≤0.09%
Bis(4-sulfobtyl) Ether Disodium	≤0.05%
Bacterial Endotoxins	≤20EU/g
The total aerobic microbial count	≤100cfu/g
The total combined moulds and yeasts count	≤50cfu/g
Escherichia coli	Absence
Clarity of Solution	30%(w/v) solution is clear and essentially free from particles of foreign matter.
Average Degree of Substitution	6.2~6.9
Peaks I-X (%peak area)	I	0.0~0.3
	II	0.0~0.9
	III	0.5~5.0
	IV	2.0~10.0
	V	10.0~20.0
	VI	15.0~25.0
	VII	20.0~30.0
	VIII	10.0~25.0
	IX	2.0~12.0
	X	0.0~4.0

PH value	4.0~6.8
Water content	≤10.0%

Function

1. Solubilization:

Neutral, positive and negative APIs can effectively combine with sulfobutyl beta cyclodextrin, which can increase the solubility of compounds with different solubility by 10 to 25000 times.

2. Convenient administration:

Sulfobutyl beta cyclodextrin has good biocompatibility and can be administered by injection, oral administration, eye, nose, external use and inhalation.


3. Good safety:

Usually, it can be quickly and completely eliminated from the kidney after administration. In vitro and in vivo acute, subacute and chronic toxicity studies provide safe data and are approved for use in human drug preparations.

4. Good stability:

The interaction with sulfobutyl beta cyclodextrin (SBCD) provides a beneficial protective environment for API in its lipophilic cavity, while the hydrophilic surface provides excellent water solubility, solubility and stability.

 

 

Packaging & Shipping

 

Packing	1kg/bag ,25kg/bag;25kg/drum; according to your requirements
Transit	Fedex, TNT,DHL,EMS,and so on.
Port	Shanghai/Tianjin/Dalian/Beijing/Xi'an
Lead Time	3-5 working days upon received the payment
	For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea.

 

Company Profile

Hefei July Biotechnology Co.,ltd is trading system gradually mature stable, scale, expanding opening flexible, the godfather management, Its marketing network, good business reputation has been praised by customers. The company has already established marketing channels with many manufactures and customers all over the world.

We are specialized in Chemical raw materials: API, Pharmaceutical intermediates, Plant extracts, Health care ingredient, Vitamin,Food additives and Cosmetic additives. These products are widely used in pharmaceutical industry, chemical industry, food industry and other industries. Welcome to consult us. Our products are widely recognized and trusted by users and can meet continuously developing economic and social needs. We welcome new and old customers from all walks of life to contact us for future business relationships and achieving mutual success!

Certifications

 

 

Exhibition

 

FAQ

1. What's the MOQ?
Usually1kg. It is based on the different product. Some are lg and some are 1 ton. Please be free to consult our salesman.
2. What's the shipping time?
If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.
3. If I need less than the MOQ, is it possible?
 Yes. Please be free to consult our salesman.
4. Can you supply the free sample?
Usually it is possible. but the shipping cost be paid bycustomers. It based on the differentproduct.Please be free to consult our salesman.
5. How to store the product?
 Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
6. What's your main payment method?
T/T, trade assurance, west union, money gram.
7: Do you have COA, MSDS, co, Health certificate, form 9 or other certificate?
 Yes, we have. pls be free to contact us to get updated one.